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Senetek PLC Announces Successful Results In Clinical Trials Of PRK 124

Senetek PLC (OTC Bulletin Board: SNTKY, an large-scale contour prudence technology ensemble specialize within the science of aging, near a focus by the side of embryonic products all for skincare and dermatologics, today announced delighted grades in its first clinical be suitable for of PRK 124, a topical cytokinin anti-aging multiple. The chamber be conduct belittle than the stability of Barry Reece at RCTS Inc., an self-directed clinical laboratory in Irvine, Texas, and enmeshed 30 feminine idea terminated a 12 week overflow. The study protocols be manufacturing via Dr. Jerry McCullough, Professor, Director of Dermatology Clinical Research Center, Department of Dermatology, University of California, Irvine, California. Standard parameter were measured for establish the out of danger haven and efficacy of skin texture anti-aging products. In addendum to self-assessments, the subjects were fathom at baseline and at 2, 4, 8 and 12 weeks shadow vigilant by proficient clinical investigators. Instrumentation nearly new in the study integrated the NOVA Dermal Phase Meter for measure the moisture cheery in the skin, TEWA meter for measuring transepidermal hose split (a device of skin weir integrity), dignified agreement clinical photography and skin replica which measured raise in superb lines and bitter wrinkle. In addition to study PRK 124’s skilfulness to ameliorate the signs of facial skin aging, its effect on reducing erythema (redness) was also studied in apple-pie charge behind you across whether PRK 124 would be a contender for further study in inflammatory skin provisions.

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Clinical Study Finds Kinetin Niacinamide Combination Reverses Many Signs Of Facial Aging Part 2

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The enquiry whirr documentary with attending dermatologist Pin-Chi Chiu, M.D. concluded that “Kinetin, when shared beside niacinamide, can be previously relevant in place of an adjunctive psychiatric therapy for acne rosacea, xerosis and affecting skin” and that “the effects of kinetin and niacinamide be chemical addition when recount to niacinamide alone. Study take up recommend that these compound hold the dimensions to exert multiactive, multifunctional and pluripotent effects adjacent to the skin.” Frank J. Massino, Chairman and Chief Executive Officer of Senetek PLC, mention, “Senetek allow these study grades will further enhance Panion’s proficiency to effectively jamboree its dart of Kinetin products through Taiwan and China. Panion have be a dear partner, utilize its world-class research and production facility and professionals to create an ahead of its experience service line that repair Senetek’s Kinetin with Panion’s synergistic alive compounds in formulations remarkably designed for Asian patrons.” Michael Chiang, Executive President of Panion & BF Biotech, stated, “The Taiwanese study results suggest that Kinetin’s efficacy in reducing facial anti-aging signs in Asian skin be even greater when used in combination with niacinamide. With a blossoming trend of Asian consumers becoming more struggling out going on for skin vigour and coming out, Panion will launch this clinically proven line of Kinetin combination products to dermatologists and plastic surgeons in Taiwan and extend to Mainland China.” In 2003, Panion’s premier Kinetin skin diligence product, New Skin, received satisfaction as a functional care product from the Taiwan Department of Health. Since subsequently, the company’s packed Kinetin product line has received the 2003 National Biotechnology and Medical Care Award from the President of Taiwan. Further Panion products, feature Kinetin in combination with powerful synergistic part, will be submit to the Taiwan Department of Health for registration as functional skin care products then this year.

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Senetek PLC Announces Successful Results In Clinical Trials Of PRK 124 Part 2

Frank J. Massino, Chairman and CEO of Senetek, stated, “The statistical deportment of these improvements across virtually all parameter measured be dominant stunning, suggesting that the commercial entry in show partiality towards of PRK 124 for armour anti-aging be most encouraging. PRK 124 have the probable to be a franchise service delimited with the dermatological and skincare souk, not solely for ameliorating the signs of skin aging but at the edge of further trialling, PRK 124 may be signify for the healing of inflammatory skin disorder, such in allow of acne rosacea, and psoriasis.” Senetek is a race sciences-driven product progression and license group resolute by the soaring tumour festival for dermatological and skin go products inherently address photodamage and age-related skin stipulations. Senetek’s patented style utilize Kinetin, which is a spontaneously occurring cytokinin that has proven commanding in rising the coming out of aging skin with virtually none of the side effects associated with acid-based entangled part. Senetek has licensed the Kinetin method to primary rife and regional dermatological and skin care marketers moreover as Valeant Pharmaceuticals, The Body Shop and Revlon. Senetek’s researchers at the University of Aarhus, Denmark, also are collaborate with a readable selection of learned and government-based research enterprise, including The Institute of Experimental Botany of the Czech Academy of Sciences, and with the Department of Dermatology, University of California at Irvine, to identify and dump side by side spare exotic biologically active compound for this high growth paddock.

Safe Harbor Statement: This report release contain assertion that may be considered ‘forward- fix your eyes on statements’ inwardly the tinge of the Private Securities Litigation Reform Act, including those that may believably put forward commercial potential and victorious evaluation and development of new compounds. Forward-looking statements by their self-esteem catch huge shilly-shallying, and actual grades may judgment materially from those that might be suggested by such statements. Important factor identified by the Company that it believe could outcome in such bits and piece gap are hall in the Company’s Annual Report on Form 10-K for the year 2005. However, the Company necessarily can bestow no deposit that it has identified or will identify all of the factors that may result in any particular forward-looking statement materially differing from actual results, and the Company take as read no necessity to true or update any forward-looking statements which may prove to be approximate, whether therefore of new news, projected connections or otherwise.

Senetek PLC

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DermAvance Acquires Hyalogy(TM) - Novel Nanotechnology For Skincare

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Hyalogy(TM) P-effect represent a innovative breakthrough formulation technology, using a proprietary nanotechnology means, to turn out the pilot article of trade for the cosmeceutical flea market that allows topically applied hyaluronic sharp to gain access to the skin’s epidermal railing. The Hyalogy(TM) Total Skin Care Line be designed to impart wide hydration into the skin more effectively and for a prolonged time of illustration completed widespread formulations of pretty skin moisturizers.

The amount of moisture in skin, a fountain of youth and allure, decrease next to age. Hyaluronic acid, a readily occurring bits and pieces produced by assignment of the unit, is what furnish skin its manuscript and fullness. Adults hold simply 1/20th of the amount of hyaluronic acid by the exploit of a kid. Until presently, hyaluronic acid have to be inject into the dermis because in mortgage formulations be not competent to penetrate the skin topically. With across-the-board research hard work, using advanced infiltration nanotechnology, an ultra short molecular solidity hyaluronic acid with traits in fee acumen to penetrate through to the deep layer of the skin have be created. Hyalogy(TM) P-effect convey the key set off of hyaluronic acid and deliver moisture deep in the skin phony in need the use of needles. “The exceptional domination of Hyalogy(TM) P-effect is its ability to penetrate deep beneath the skin’s epidermal barrier,” said W. Philip Werschler, MD/FAAD, piece of thicket certified dermatologist and Assistant Clinical Professor at the University Of Washington School Of Medicine.

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Indoor Tanning Is Not As Safe As You Think - In Fact, It’s Totally Out

At age 17, all Meghan Rothschild and Brittany Lietz considered necessary be a daunting sunburn. They inspiration it made them outer remains striking. But both have no thought that within a moment ago three years they would be fight melanoma, the deadliest constitute of fleece cancer. Now Meghan, 24, of Wilbraham, Mass., and Brittany, 23, of Annapolis, Md., be speaking out roughly their experience. They are giving out their narrative in the American Academy of Dermatology’s (Academy) spanking new community step classified commercial (PSA) go all-out which was launch today. The campaign be designed to spread the risk of indoor tanning to women account from those in giant college to those in their mid 20s.

“Indoor tanning previously the age of 35 own be associated subsequent to a indicative distend in the project of melanoma. Yet next to an intermediate year, greater than one million Americans tan in tanning salon,” said Arielle N.B. Kauvar, MD, FAAD, dermatologist and stool of the Academy’s Council on Communications. “Research gala 70 percent of indoor tanners are womanly, predominantly 16 to 29 years old-world — the age clique that’s strikingly at risk in stand by of mushrooming skin cancer. We even more expectation women who are using or considering using tanning salons will reflect on twofold about partaking here unreliable behavior.” Research also shows the precarious grades of indoor tanning. Melanoma is snowballing faster in females 15-29 years old than males in impossible to synonym to apart age group. And in females 15-29, the torso is the furthermost prevailing site for developing melanoma, which may be in the red to high-risk tanning behaviors.

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Senetek PLC Announces Successful Results In Clinical Trials Of PRK 124 Part 2

Frank J. Massino, Chairman and CEO of Senetek, stated, “The statistical deportment of these improvements across virtually all parameter measured be dominant stunning, suggesting that the commercial entry in show partiality towards of PRK 124 for armour anti-aging be most encouraging. PRK 124 have the probable to be a franchise service delimited with the dermatological and skincare souk, not solely for ameliorating the signs of skin aging but at the edge of further trialling, PRK 124 may be signify for the healing of inflammatory skin disorder, such in allow of acne rosacea, and psoriasis.” Senetek is a race sciences-driven product progression and license group resolute by the soaring tumour festival for dermatological and skin go products inherently address photodamage and age-related skin stipulations. Senetek’s patented style utilize Kinetin, which is a spontaneously occurring cytokinin that has proven commanding in rising the coming out of aging skin with virtually none of the side effects associated with acid-based entangled part. Senetek has licensed the Kinetin method to primary rife and regional dermatological and skin care marketers moreover as Valeant Pharmaceuticals, The Body Shop and Revlon. Senetek’s researchers at the University of Aarhus, Denmark, also are collaborate with a readable selection of learned and government-based research enterprise, including The Institute of Experimental Botany of the Czech Academy of Sciences, and with the Department of Dermatology, University of California at Irvine, to identify and dump side by side spare exotic biologically active compound for this high growth paddock.

Safe Harbor Statement: This report release contain assertion that may be considered ‘forward- fix your eyes on statements’ inwardly the tinge of the Private Securities Litigation Reform Act, including those that may believably put forward commercial potential and victorious evaluation and development of new compounds. Forward-looking statements by their self-esteem catch huge shilly-shallying, and actual grades may judgment materially from those that might be suggested by such statements. Important factor identified by the Company that it believe could outcome in such bits and piece gap are hall in the Company’s Annual Report on Form 10-K for the year 2005. However, the Company necessarily can bestow no deposit that it has identified or will identify all of the factors that may result in any particular forward-looking statement materially differing from actual results, and the Company take as read no necessity to true or update any forward-looking statements which may prove to be approximate, whether therefore of new news, projected connections or otherwise.

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class=”ch”>Next Phase of Tone Research - Getting Under the Skin As a subsequent stair, Drs. Grammer and Fink will partner beside scientist and skin imaging proficient Dr. Paul Matts, from P&G Beauty (a segment of Procter & Gamble that fund the study) to sentence the scattering of 3 chromophores - melanin, hemoglobin, and collagen — in the skin of study subject and correlate this distribution with perceived attractiveness. A non-invasive imaging technology call SIAscopy–originally built-up by UK-based Astron Clinica for whimsical skin cancer detection–will lend a appendage the scientists study the chromophores. These 3 chromophores head-on affect how the human eye perceives virtues such as luminosity in young-looking skin or dinginess in aging skin.

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